抄録
Accumulation and elimination of 14C-labelled Sodium 5-(acetylamino)-3, 5 dideoxy-D-glycero-D-galacto-2-nonulosonate (KI-111) were studied in rats after 7 or 14 repeated subcutaneous (s.c.) administration, by measurement of the tissue level and whole body autoradiography. At 15 minutes after final s. c. administration of the compound, the radioactivity was observed in all tissues and organs except the brain and spinal cord. High radioactivity was observed in the injected site, kidney and circulating blood. At 24 hours after administration, the radioactivity was observed in the injected site, kidney and intestine.
