Abstract
A spayed 10-year-old American shorthair cat with repeated wheezing was suspected to have asthma. Serum antigen specific IgE test showed that the cat was slightly positive against pollen allergens of Lolium perenne and Fascue meadow. Eosinophil counts were high in both the peripheral blood and the bronchoalveolar lavage fluid. A provocation test was performed using pollen/grass allergen mixture (seven grasses including Lolium perenne and Fascue meadow.), double-blind-wise and randomly, and the asthmatic cause was confirmed. Therefore, rush intranasal hyposensitization therapy was performed using this allergen mixture. Six months after the hyposensitization was started, the clinical condition of the cat became stable. In this case, there was a correlation (r = 0.74) between the percentage of eosinophile in the peripheral blood and the frequency of asthmatic attacks.