Epilepsy & Seizure
Online ISSN : 1882-5567
ISSN-L : 1882-5567
Brief Communication
Detection of slightly increased signals in temporal lobe on periictal arterial spin labeling perfusion image for initial suspicion of temporal lobe epilepsy
Hiroshi OketaniTakato MoriokaSatoshi InohaKenji MikiTakafumi ShimogawaNobutaka MukaeAyumi SakataHiroshi ShigetoKoji Yoshimoto
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ジャーナル フリー

2023 年 15 巻 1 号 p. 67-74

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Introduction: Magnetic resonance (MR) perfusion imaging with arterial spin labeling (ASL) can easily detect periictal hyperperfusion accompanying epileptic seizures. Herein, we report two cases in which ASL performed immediately after a seizure was useful for the initial suspicion of temporal lobe epilepsy (TLE).

Case report: Patients 1 and 2 developed focal-to-bilateral tonic-clonic and focal impaired awareness seizures, respectively, and were subsequently transferred to our facility for out-of-hours service. On emergent ASL MR perfusion imaging, a slight increase in signals from the hippocampus and lateral temporal lobe was observed in both patients. However, routine electroencephalography (EEG) performed from 12 h to two days later showed corresponding paroxysmal discharges only in Patient 2.

Conclusion: These cases suggest that MR imaging with ASL perfusion, which can be performed 24 hours a day, is useful for the initial suspicion of TLE, compensating for the limitation of routine EEG. However, to ensure a definitive diagnosis, it is important to evaluate the result together with clinical history, seizure semiology and findings of other modalities centered on EEG.

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© 2023 The Japan Epilepsy Society
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