Electrochemistry
Online ISSN : 2186-2451
Print ISSN : 1344-3542
ISSN-L : 1344-3542
Headline
Electrochemical Microbiosensors Using Living Cells
Tomokazu MATSUEHitoshi SHIKU
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JOURNAL FREE ACCESS

2006 Volume 74 Issue 2 Pages 107-113

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Abstract

This article describes recent progress of cell-based electrochemical biosensors, especially focusing on the incorporation of micro-fabrication technology and gene-modified engineering. Modern electroanalytical techniques offer extremely low detection limits that are achievable using small sample volumes. Bio-MEMS (bio-micro-electromechanical system) technology allows on-line monitoring of cellular functions in which various analytical operations with microfluidics. Reporter gene systems are frequently used in gene-expression studies and applied to environmental monitoring and food safety analyses. These research trends have clearly demonstrated that electrochemical whole-cell devices will have strong impacts on modern biotechnology and become an indispensable tool to ensure the safety of our society.

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© 2006 The Electrochemical Society of Japan
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