STUDIES ON THE ABERRATION OF THE FUNCTIONS
ESPECIALLY THE FUNCTIONAL ALTERATION OF TESTIS CAUSED BY THE REPEATED INJECTION OF TESTICULAR EMULSIONS
1950 Volume 26 Issue 9 Pages 221-231
Details
1950 Volume 26 Issue 9 Pages 221-231
The writer has studied the change of testicular function influenced by repeated irritations and has obtained the following results:
1) The rabbit shows a decrease of serum calcium when 5% testicle-emulsion of the rabbit is injected, but when it is repeatedly injected over 15 times, it begins to show no reaction and during this time an active substance appears in the ear vein.
The function of the active substance brings on the atrophy of the testicle of the mice and stops development of the testicle and the cockscomb of the cocks. The active substance appears earlier, and in/greater quantity in the serum of Vena spermatica interna and in the testicle than in the ear vein of the rabbit. And if the testicle is removed, this substance is vanished from the blood.
2) The character of this active substance is a protein of globulin fraction and when the above so altered terticle is retransplanted to another body, the same substance appears in the blood.
Therefore it is believed that this sunstance is a product produced by the qualitative alteration of the testicular function.
From the above experiment is believed that the repeated injections of the organ-emulsion always makes the function of the concerned organ alter qualitatively.
