日本内分泌学会雑誌
Online ISSN : 2186-506X
Print ISSN : 0029-0661
ISSN-L : 0029-0661
Cushing氏症候群の2例
横尾 定美関口 孟男佐伯 普飯塚 道彦
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1957 年 33 巻 6 号 p. 513-518,493

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The Cushing's syndrome has following symptomes, they are excess of fat which appears especially on trunk, face and neck, full moon face, hypertension, hypertrichosis, striae cutis disensae, suger metabolism disturbance, osteoporosis, myasthenia, decubitus ulcer, and in female case, menoxenia.
We recently had female & male cases which considered to be cushihg's syndrome.
1) The female case; 45 years old unmarried school teacher complaind of abnormal fat excess of neck & trunk and palpitation. Through out her physical investigations, we got followng data, they are, excess of fat on neck & trunk, full moon face, hypertension, hypertrichosis, striae cutis distensae, desubitus ulcer, decrease of lymphocyte & eosinophilic leukocyte, plethora, increase of serum K & Cl and menoxenia. We couldn't prove increase of 17 OHCS & 17 KS in urine and osteoporosis.
2) The male case; 48 years old man, has no hereditary disease and past anamnesis, complaind of slight headache, languourous legs & concequently, dysbasia. Objective view of this patient are as following, fatty obesity, full moon face, hypertension, plethora, suger metabolism disturbance, slight hyperglycemia, myasthenia and decrementum of sexual impuls. And we also couldn't prove osteoporosis, hypertrichosis and striae cutis distensae.

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