A STUDY OF ADRENAL REGENERATION HYPERTENSION

EFFECT OF THE DELAYED ADRENAL ENUCLEATION ON THE DEVELOPMENT OF HYPERTENSION AND SALT APPETITE

Abstract

The relation between the salt intake and the time of adrenal enucleation in Skelton's hypertension was investigated.
Neither increase of salt nor elevation of the blood pressure into hypertensive range occurred, if there is a 2-weeks-interval between the uninephroadenalectomy and the contralateral adrenal enucleation.
Under the same procedure increasing the concentration of sodium chloride in the drinking fluid to 2% caused increase of salt intake, but it brought the animals into the state of salt intoxication without hypertension.
The reasonable explanation for these results remains unresolved.