Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
STUDIES ON β-PAROTIN III. ACTIVATION OF INACTIVE β-PAROTIN BY THE INCUBATION
STUDIES ON THE PHYSIOLOGICAL CHEMISTRY OF THE SALIVARY GLANDS LXVI
YOSOJI ITOSASHICHI OKABESHUICHI NAMBA
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1965 Volume 12 Issue 2 Pages 78-82

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Abstract

Crude and purified β-parotin obtained from fresh parotid gland were biologically inactive, while the same products obtained after the autolysis of the gland were active. However, it was found that the inactive material could be easily activated by the incubation at 37°C; the most suitable condition was 24 to 48hrs. incubation at pH 5.5 in an aqueous solution.
Although the mode of activation is still remained to be clarified, it seems to occur without an activator, because the activation was observed even with a highly purified material.

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© The Japan Endocrine Society
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