When, PMS heterogenous gonadotrophin, was administered to the amenorrhoeic women, the rate of pregnancy was not so high despite considerable high rate of ovulation. This has been a question up to date.
Recently we performed combined gonadotrophin therapy of PMS and HCG on a 27-years-old woman with grade II secondary amenorrhoea, and succeeded in inducing ovulation. But owing to overstimulation by PMS and HCG therapy, she developed complication of acute abdomen. Thereupon laparotomy was performed to carry out wedge resection on the ovary. At the time of this induced ovulation, the patient succeeded in pregnancy which continued until term inspite of the ovarian operation. At term she was delivered of a normal child. We made some comments on this case.