A STUDY OF MECHANISMUS BY WHICH COPPER SALTS INDUCED OVULATION IN THE RABBIT

Abstract

It has been confirmed that the copper-induced ovulation is inhibited eventually by the barbiturate, just as the picrotoxin induced one. This fact would be enough to verify the nervous mechanism exerted by copper molecule, after being transmitted to the hypothalmic area essentially by a. vertebralis. The functional close link between a. vertebralis and the hypothalamus is indicated by the predominant effectiveness of the intravertebral injection of copper in eliciting ovulation. The significance of this vessel concerning the steroid control of the pituitary in the reproductive cycle was discussed.