Abstract
The various biological responses which were observed by the intravenous injection of SPA were now studied by the oral administration of SPA.
About 10% reduction of serum calcium level was elucidated with the dose of 2 to 5mg per kg of body weight, however, the number of the circulating leucocyteswas not affected by this treatment.
The promotion of the calcification in the dentine of rabbit incisor was also observed by the oral administration of 0.5mg per kg of body weight of SPA.
The potent uro-parotin was excreted in the urine for short period after the oral administration of a considerable amount of SPA in the sialoadenectomized rabbits.
From these results, it was confirmed that the oral administration of the adequate doses of SPA causes the various biological functions which have been found with the parenteral administration of SPA.
