Abstract
Radioactive iodine labelled saliva-parotin-A (131I-SPA) was administered to rats by forced feeding or by injection into the ligated intestine in order to study its passage across the intestine. Higher radioactivity localization was found in the kidney as compared to control rats given KI-131I in the same method. The presence of 131I-labelled macromolecules in serum was elucidated by the following procedures: phosphotungustic acid precipitation, radio-paper-chromatography and gel filtration with Sephadex G-75. From the results of the present investigation and those reported previously in this proceeding, the possibility of passage of saliva-parotin-A (SPA) across the intestine was raised.
