Abstract
Serum LDH activity was found to be elevated in 16 out of 20 patients with Cushing's syndrome. This elevation was mainly due to increased LDH1 and LDH2, and correlated with the levels of urinary 17OHCS. When the glucocorticoid excess was corrected by surgery, elevated serum LDH levels tended to be normal. Thus, it was concluded that elevated serum LDH is a common finding in Cushing's syndrome and glucocorticoid excess may cause tl-e elevation of LDH by some undetermined mechanism.
