Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
Inhibition of Thyroxine-Induced Metamorphosis by Prolactin in Tadpoles, Rana Catesbeiana
TAKEHIKO NOGUCHISAKAE KIKUYAMA
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1979 Volume 26 Issue 5 Pages 617-621

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Abstract
Thyroxine (T4)-prolactin interactions on hepatic arginase and ornithine transcarbamylase (OTC) as well as hind legs, tail, digestive tract and median eminence were investigated in tadpoles, Rana catesbeiana.
Prolactin completely blocked T4-induced tail resorption, but failed to suppress hind-leg growth, shortening of digestive tract and promotion by T4of the median eminence development. Prolactin blocked T4-induced increase in hepatic arginase activity but not in hepatic OTC activity.
A possibility that T4and prolactin are regulating the hepatic arginase indirectly is discussed.
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© The Japan Endocrine Society
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