Abstract
1. Measurement of ascorbic acid content of adrenal medulla of the pig and horse rendered the values of 1.99 and 2.08mg per g wet wt.respectively. These values are comparable with the values for the adrenal cortex, and represent the highest among the values in all the tissues submitted to measurement.
2. It was learned that, so far as a certain amount of reduced ascorbic acid is present in the adrenal medulla homogenate, oxidation of adrenalin does not take place.
3. Autoxidation and oxidation of adrenalin through the agency of cytochrome system are inhibited by the addition of ascorbic acid, and the rate of inhibition is parallel with the concentration of the latter.
4. Data were presented and discussed to the effect that ascorbic acid found abundantly in the adrenal medulla would possibly be concerned with protection from oxidation of high concentration of adrenalin at its site of elaboration.
