STUDIES ON THE SALIVARY GLAND HORMONE XXXIV INFLUENCE OF TRYPSIN ON PAROTIN (1)

Abstract

The influence of tryptic digestion on the biological activities of Parotin, the salivary gland hormone, were determined. The serum calcium level decreasing activity of Parotin was slowly diminished and almost destroyed after digestion for 24 hrs. by trypsin. The decreasing activity on the number of circulating leucocytes was rapidly diminished while the increasing acitivity of leucocytes was relatively resistant to the action of trypsin, and remained even after digestion for 24 hrs. The total serum protein decreasing activity of Parotin was not comparatively diminished by trypsin, and was shown no significance between digesting time and the activity.