Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
INFLUENCES OF VARIOUS CHEMICAL REAGENTS ON THE BIOLOGICAL ACTIVITIES OF S-PAROTIN
STUDIES ON SUBMAXILLARY GLAND XII
SHIGERU AONUMATAKAO HAMAHIROKO HONDAYOSOJI ITOMASATO SHINODA
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1958 Volume 5 Issue 4 Pages 256-264

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Abstract
The activities of S-Parotin in aqueous solution were relatively stable against acid and alkaline. In solid state, S-Parotin could be stored for 4 years at room temperature without any remarkable loss of the activity. The activities reversiblly denaturated by urea. Ca-decreasing activity received non-reversible denaturation by guanidine hydrochloride, but Leucocytes decreasing and then increasing activity did not receive any denaturation. From the results of S-Parotin treated with nitrous acid, formaldehyde, iodine, cysteine and thioglycollic acid, it could concluded that there is no particularly responsible radical for the display of activities and the free amino radical and the tyrosine phenyl radical are responsible.
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© The Japan Endocrine Society
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