Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
THE EFFECT OF SPLANCHNIC NERVE STIMULATION ON ADRENOCORTICAL SECRETION
SHIGEO OKINAKAHIROSHI IBAYASHIKENJI MOTOHASHITAKUO FUJITASHO YOSHIDANAKAAKI OHSAWA
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1960 Volume 7 Issue 1 Pages 19-24

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Abstract
Secretion of 17-hydroxycorticosterone and corlicosterone from adrenal venous blood of a dog was investigated using Bush's benzene-methanol-water system of paper chromatography. Stimulation of splanchnic nerve resulted in a significant increase of 17-hydroxycorticosterone and decrease of corticosterone resulting in a marked increase of F/B ratio. This effect was abolished by hypophysectomy and restored by maintenance with ACTH. Stimulation of 17-hydroxylation in adrenal cortical hormone biosynthesis is suggested as the mechanism of splanchnic nerve action.
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© The Japan Endocrine Society
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