Abstract
Glycogenetic effect of 1mg of subcutaneous serotonin was demonstrated in diaphragm of glucose fed adrenodemedullated rats. The effect was shown to be additive to the action of 0.02 I. U. of glucagon-free insulin given intravenously. Failure of subcutaneous serotonin to increase cardiac glycogen was also noted, while insulin significantly increased it. The difference of serotonin effect by administration route and possible interrelations between serotonin and insulin were briefly discussed on peripheral utilization of glycogenic substance.
