Morphometric Study on the Fetal Thyroid Gland in the Nude Mouse (BALB/cAnNCrj-nu/nu)

Tomo INOMATA; Hiroyoshi NINOMIYA; Shizuo KAWAKAMI; Kazuko SAKAGUCHI; Katsuyasu SAKITA; Satoko AOYAMA; Mitsuyuki SHIRAI; Toshio MASAOKA; Fumiaki AKAHORI

doi:10.1538/expanim.45.385

Note

Morphometric Study on the Fetal Thyroid Gland in the Nude Mouse (BALB/cAnNCrj-nu/nu)

Tomo INOMATA, Hiroyoshi NINOMIYA, Shizuo KAWAKAMI, Kazuko SAKAGUCHI, Katsuyasu SAKITA, Satoko AOYAMA, Mitsuyuki SHIRAI, Toshio MASAOKA, Fumiaki AKAHORI

Author information

Tomo INOMATA
Department of Laboratory Animal Science, School of Veterinary Medicine, Azabu University
Hiroyoshi NINOMIYA
Department of Laboratory Animal Science, School of Veterinary Medicine, Azabu University
Shizuo KAWAKAMI
Department of Theriogenology, School of Veterinary Medicine, Azabu University
Kazuko SAKAGUCHI
Public Health Administration, College of Environmental Health, Azabu University
Katsuyasu SAKITA
Department of Laboratory Animal Science, School of Veterinary Medicine, Azabu University
Satoko AOYAMA
Department of Laboratory Animal Science, School of Veterinary Medicine, Azabu University
Mitsuyuki SHIRAI
Department of Veterinary Pharmacology, School of Veterinary Medicine, Azabu University
Toshio MASAOKA
Department of Veterinary Pharmacology, School of Veterinary Medicine, Azabu University
Fumiaki AKAHORI
Department of Veterinary Pharmacology, School of Veterinary Medicine, Azabu University

Keywords: BALB/c-nu/nu, fetus, thyroid gland

JOURNAL FREE ACCESS

1996 Volume 45 Issue 4 Pages 385-388

DOI https://doi.org/10.1538/expanim.45.385

Details

Abstract

Fetal thyroid glands of athymic nude mice (BALB/cAnNCrj-nu/nu) were examined morphometrically on day 18 of gestation. Compared to euthymic litter mate controls (BALB/cAnNCrj-nu/+), both the cell height and diameter of thyroid follicles were significantly smaller; fewer well-developed follicles were found in the peripheral region of the thyroid; the body weight and total volume of the thyroid gland were also smaller in nude mice. These results suggest underdevelopment of the fetal thyroid gland of the athymic nude mouse.

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