Experimental Animals
Online ISSN : 1881-7122
Print ISSN : 1341-1357
ISSN-L : 0007-5124

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Canine regional gastric blood flow measurement using perfusion computed tomography
Kazuya KUSHIDAMiu MATSUMOTOMizuki TAMAZAWAKentaro YAMAZAKIEisei SHIMIZUAiri KANEYAMAAritada YOSHIMURAShunsuke MIYAHARAKodai TASHIROKija LEEMasaaki KATAYAMARyuji FUKUSHIMAMiori KISHIMOTO
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ジャーナル オープンアクセス 早期公開

論文ID: 24-0134

この記事には本公開記事があります。
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This study aimed to determine the feasibility of using perfusion computed tomography (CT) to assess blood flow in different regions of the stomach in dogs. Dynamic perfusion CT scans were conducted on five beagle dogs, and blood flow analysis was performed using the maximum slope and Patlak plot methods. The findings revealed significant variations in blood flow among the fundus, body, and pylorus of the stomach. Specifically, the body showed approximately 1.3 times higher blood flow than the fundus and approximately 5 times higher blood flow than the pylorus. There were no significant differences in blood flow between the two analysis algorithms. The findings suggest that gastric perfusion CT can accurately detect variations in blood flow within the stomach. Using the maximum slope method for analysis allows for noninvasive and rapid measurement of gastric blood flow. This technique may have clinical applications in detecting submucosal diseases that are challenging to identify with endoscopies and serve as a valuable noninvasive tool for longitudinal observations in experimental animal studies.

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