HEMORRHAGIC LIPEMIA IN HYPOXIC RABBITS: DIFFERENCES BETWEEN TWO DIETARY CONDITIONS

Abstract

High serum lipid levels were obtaind in rabbits by consecutive daily bleeding with increasing volume over a six day period. The diet during breeding was shown to have a considerable effect on the elevation of lipids by use of rabbits fed on two dietary conditions. Biochemical analysis of serum and histological observations revealed the relation between the decrease of numbers of erythrocyte and the daily changes in the serum lipid and protein levels, and it was supported that hemic hypoxia results in an ischemia of whole cells and tissues.
Such hemorrhagic lipemia coupled with the improved method of bleeding in the rabbits under a controlled natural dietary condition may be used as a model for certain hypoxic diseases.