Linkage of the Analbuminemia Locus (alb) and the Hooded Locus in the Rat, Rattus Norvegicus

Abstract

A linkage study of the analbuminemia (alb) with some coat color loci (a, b, c, h) has been carried out by crossing the analbuminemic random-bred mutant NAR strain with the abh tester strain of rats, the Agouti-Irish inbred ACI strain and the Agouti-Nonhooded inbred IS strain. The analbuminemia (alb) locus is not linked to a, b, and c loci but linked to hooded locus from F2 and backcross progeny of the F1 hybrids of abh x NAR, ACI x NAR and IS x NAR to NAR. Recombination value between alb and h was 16.4±2.3 per cent from the data of F2 and backcross progeny of (ACI x NAR) F1 and (IS × NAR) F1 to NAR. This is the third locus on the sixth linkage group of the rat.