Influence of Repeated Oscillation Stress in Rats

Abstract

The influence of two weeks of repeated oscillation stress on rats was investigated. Organ weights, liver glycogen, adrenal ascorbic acid, hematological and serum biochemical analysis and maximum contraction of vas deferens induced by noradrenaline were measured. In stress-loaded rats, body weight fell to 85-90% compared with control rats. Atrophy of the thymus and hypertrophy of the adrenals were found in stress-loaded rats. Hematological and serum biochemical findings revealed that white blood cells and blood glucose decreased, but NEFA increased significantly. Serum sodium increased, but potassium decreased. Maximum contraction of vas deferens induced by noradrenaline was potentiated in stress-loaded rats. The other findings did not differ from those of controls. From these results, it is suggested that the stress-loaded rat shows some abnormalities, but may adapt partially to stress.