Investigation of Nitroblue Tetrazolium Reduction of Neutrophils in the Dog Infected with Hepatozoon canis

Abstract

Investigation of nitroblue tetrazolium (NBT) reduction of neutrophils was performed in the dog infected with Hepatozoon canis. No positive reactions were observed in the parasitized neutrophils by the resting and the stimulated NBT reduction tests. However, results of resting and stimulated NBT reduction tests apparently made no differences between non-parasitized neutrophils of the infected dogs and neutrophils of the non-infected dogs. These findings show that the parasitized neutrophil has no oxidative bactericidal capacity and the infected dogs had no-change in the host protective mechanism.