Experimental Animals
Online ISSN : 1881-7122
Print ISSN : 0007-5124
Localization of a N-ras-related Sequence on Rat Chromosome 1
Tetsuo KUNIEDAEiji KOBAYASHIMotokazu TACHIBANATomonori IMAMICHIYutaka TOYODA
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Keywords: linkage, rat, N-ras, RFLP
JOURNAL FREE ACCESS

1994 Volume 43 Issue 1 Pages 125-127

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Abstract

Location of the locus for a restriction fragment length polymorphism of N-ras-related sequences (NRAS2) on the rat chromosome 1 was determined by linkage analysis using a microsatellite locus (KAL) and a coat-color locus (C) . The recombination frequencies between NRAS2 and C, NRAS2 and KAL, and C and KAL in 57 backcross progeny obtained from crosses of (WKS/Iar x IS/Iar) x WKS/Iar were 7.0±3.4%, 28±5.9%, and 23±5.6%, respectively. The order of the three loci on the rat chromosome 1 was determined as follows : KAL-C-NRAS2.

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© Japanese Association for Laboratory Animal Science
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