Abstract
Lactobacillus acidophilus L-92 (L-92) has been selected as a lactic acid bacterium expected to have anti-allergic function. We showed that ingestion of foods containing L-92 could alleviate allergic symptoms caused by type I allergic reactions such as perennial allergic rhinitis or atopic dermatitis in human clinical trials. In this article, we report the effects of oral administration of L-92 on symptoms of pollen allergy.
Subjects ingested tablets containing 20.7 mg of L-92 per day for 12 weeks and assessed their nasal and ocular symptoms scores every day. As a result, the sneeze scores showed significantly lower level compared to the placebo group at 12 weeks. In addition, the itch eye score and ocular symptom-medication score were significantly compared to the placebo group during the test period. Antigen - specific IgE level in L-92 group was reduced compared with the placebo group in the 12-week period.
These results show that oral administration of L-92 could alleviate the symptoms of pollen allergy.
