Nippon Yakubutsugaku Zasshi (Folia Pharmacologica Japonica)
Online ISSN : 2185-307X
Print ISSN : 0369-4461
ISSN-L : 0369-4461
Relation between the Urine Quantity and the Modes of Administration of Ringer-Locke's Solution.
Susumu Uyeda
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1927 Volume 4 Issue 3 Pages 300-308

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Abstract
The author determined the urine quantities in rabbits for eight hours after introducing Ringer-Locke's solution into the vein, the subcutaneous tissue, the peritonial cavity, the stomach or the rectum and obtained the following facts :
If 50 c.c. Ringer-Locke's solution per kilogram is administered to a rabbit, an increase of the urine quantity can evidently be seen only in the intravenous infusion. Peroral administration of 50 c.c. water, however, induces also a slight increase of it. After injecting 200 c.c. of Ringer-Locke's solution per kilogram, an augmentation of the urine amount is always proved in all the modes of administration. This is, then, most marked in the intravenous infusion, next in the subcutaneous injection, and then in the intraperitoneal application.
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