Abstract
The toad's brain was succesively destroyed downwards in several parts and the effects on the posterior lymphatic heart-beat investigated. As a result it was found that the most striking effect was observed in the case of the destruction of the optic lobe and the medulla and that it was quite contrary to each other. When the central analeptics ware applied on the optic lobe, the tone of the lymphatic heart was increased and by the application of the central depressants it was decreased, but when applied on the medulla, the effects of both series of drugs were quite opposite to each other. Thus the presence of the higher centres which control the lymphatic heart-beat was suggested, the accelerating center being on the optic lobe while the inhibitory was on the medulla.
