Multimodal Bioimage Sensor

Kazuaki SAWADA; Hirokazu NAKAZAWA; Shoko TAKENAGA; Takeshi HIZAWA; Masato FUTAGAWA; Fumihiro DASAI; Takashi SAKURAI; Koichi OKUMURA; Toshiaki HATTORI; Makoto ISHIDA

doi:10.1587/transfun.E97.A.726

Special Section on Analog Circuit Techniques and Related Topics

Multimodal Bioimage Sensor

Kazuaki SAWADA, Hirokazu NAKAZAWA, Shoko TAKENAGA, Takeshi HIZAWA, Masato FUTAGAWA, Fumihiro DASAI, Takashi SAKURAI, Koichi OKUMURA, Toshiaki HATTORI, Makoto ISHIDA

Author information

Kazuaki SAWADA
Toyohashi University of Technology
JST CREST
Hirokazu NAKAZAWA
Toyohashi University of Technology
Shoko TAKENAGA
Toyohashi University of Technology
Takeshi HIZAWA
Toyohashi University of Technology
Masato FUTAGAWA
JST CREST
Fumihiro DASAI
Toyohashi University of Technology
Takashi SAKURAI
JST CREST
Koichi OKUMURA
Toyohashi University of Technology
Toshiaki HATTORI
JST CREST
Makoto ISHIDA
Toyohashi University of Technology

Keywords: bioimaging, CCD, pH sensor, acetylcholine, ion

JOURNAL RESTRICTED ACCESS

2014 Volume E97.A Issue 3 Pages 726-733

DOI https://doi.org/10.1587/transfun.E97.A.726

Details

Abstract

To visualize the biochemical distribution two-dimensionally, we invented a solid-state-type ion image sensor that indicates the chemical activity of solutions and cells. The device, which consists of a CCD array covered with a functionalized membrane to detect charge accumulation, is highly sensitive to changes in the concentration and two-dimensional distribution of ions and biomaterials.

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