Abstract
The effects of adrenaline on the blood pressure. of rabbit, when it is injected into the ear-vein or in the pulmonary artery as well as in the left ventricle, or when sprayed on the bronchial walls directly, were studied. Also, adrenaline, ephedrine, benadryl, and atropine were sprayed on the bronchial walls and the minimal effective doses which were able to relax the bronchial muscles constricted by the preliminary spraying of histamine or acetylcholine were determined. From the results it was concluded that no adrenaline is destroyed in the pulmonary vessels while about a half of the dose is destroyed in the regions between the pulmonary vessels and the lung tissues and about 80 to 90 per cent is destroyed in the bronchial tissues.
