Pharmacological stuaies on the function of extrapyramidal system.

Report II. Significance of hypothalamus, mid-brain and cerebellum in the presence of extrapyramidal poisons

Abstract

Using mice as in the first report (see this Breviaria No. 4) hypothalamus and mid-brain were sectioned independently into four portions by the high frequency electrocautery, while the vermis of cerebellum was destroyed either on one or on both sides. The injury on hypothalamus and mid-brain, especially on the ventral portion of their both sides caused a noticeable inhibition against the action of extrapyramidal poisons, whereas the partial injury on midbrain or on cerebellum seemed, however, to have no direct effect on these poisons.