Abstract
The groups of rats injected a convulsive dose Qf nicotine (5 mg/kg) once a day for 30 to 120 days were compared with those of untreated with examination on the following : (1) convulsion induced by nicotine, (2) effect of nicotine on the cellular respiration of cerebral cortex, liver and kidney, and (3) nicotine inactivation by liver. As the results it was proved that no significant difference between both groups of animals could be found.
