Abstract
Cholinesterase activity was determined with manometric techniques on tissues of cats which had succumbed to poisoning of digitoxin, g-stropharithin and convallatoxin. Results obtained were as follows : Digitoxin inhibits cholinesterase of serum, auricle, ventricle and medulla oblongata. g-Strophanthin and convallatoxin reduce cholinesterase of ventricle markedly and that of auricle slightly, but have no effect on cholinesterase in medulla oblongata. The 3 glycosides have no influence on cholinesterase of brain cortex. In cats from which liver has been blockaded from blood circulation, digitoxin produces more prominent inhibitory action on cholinesterases of serum and tissues than in normal cats.
