Abstract
In this paper is described an experimental study of GA-56 which was developed to improve lipid metabolism regarding teratogenic effect. The mother's condition (general appearance, body weight), pregnancy status by Cesarean section (dead fetuses, body weight, sex ratio, gross and skeletal malformation) and fetal appearance after a natural delivery (pregnant periods, number, growth and nursing ratio) were all examined. In both mice and rats administered 8, 000 mg/kg of GA-56, there was an inhibition of increasing body weight and a slight increase in dead fetuses. In the groups on 500 mg/kg and 2, 000 mg/kg no effect on the mother's condition, pregnancy status and delivered fetal appearance was observed.
