Abstract
Effects of adrenaline derivatives such as adrenaline, Meta-proterenol and Butyl-sympatol on the heartlung preparation were investigated and compared. Results are as follows: Ethyl-adrianol, Metaproterenol and Butyl-sympatol showed positive inotropic and chronotropic action on the heart-lung preparation of the dog. The increasing order of cardiac activity of adrenaline derivatives was as follows: isoproterenol adrenaline noradrenaline Metaproterenol Ethyl-adrianol Butyl-sympatol. These actions were blocked by propranolol, but not by phenoxybenzamine.
