Abstract
On endoscopy, a 60-year-old man was found to have a lower esophageal ulceration. In particular, the lesion belonged to the IIa+IIc type ; the lesion was located on the right anterior wall of the lower esophagus, and involved a short segment at Barrett's epithelium. On biopsy, it was diagnosed as a poorly differentiated adenocarcinoma. A sub-total esophagectomy was performed. On histology of the resected specimen, a poorly differentiated adenocarcinoma located at the IIc area of the tumor and a well to moderate differentiated adenocarcinoma located at the IIa area of the tumor were diagnosed. The lesion was 13×18 mm in size. The lesion originated in the short segment Barrett's esophagus, and massive submucosal invasion (sm2) without lymph node metastasis was noted.