A CASE OF MANTLE CELL LYMPHOMA WITH SUBMUCOSAL TUMOR-LIKE ELEVATION OF THE APPENDICEAL ORIFICE

Abstract

A 70-year-old man was referred to our hospital because of multiple nodules in both lungs. Colonoscopy revealed multiple lymphomatous polyposis (MLP) and submucosal tumor-like elevation of the appendiceal orifice. Based on the histopathological findings, fluorescence in situ hybridization (FISH), whole body computed tomography (CT), fluorodeoxyglucose-positron emission tomography (FDG-PET), and bone marrow examination he was diagnosed as having mantle cell lymphoma (Ann Arbor StageIVA). Complete remission was achieved after 4 courses of rituximab plus chemotherapy. The patient remained disease-free at 6 months after treatment.