A CASE OF PYOGENIC GRANULOMA OF THE ESOPHAGUS PRESENTING WITH A POLYPOID LESION ON A SUBMUCOSAL TUMOR-LIKE BASE

Abstract

The patient was a 66-year-old female who complained of dysphagia. Upper gastrointestinal endoscopy showed a pedunculated polypoid lesion covered with a whitish lining based on a submucosal tumor-like protrusion in the thoracic esophagus. Biopsy specimens revealed a lobular architecture under the normal squamous epithelium. Immunohistochemical analysis demonstrated Factor VIII and CD31 in the tumor cells and suggested the lesion was a type of hemangioma. The lesion was diagnosed as a pyogenic granuloma of the esophagus, and endoscopic submucosal dissection was performed. Although pyogenic granuloma is benign, endoscopic treatment is recommended because of the risk of hemorrhage. Cases of pyogenic granuloma of the esophagus are rare, and to our knowledge, only 16 cases including our case have been reported in Japan. This is the first case presenting a POLYPOID LESION on a SUBMUCOSAL TUMOR-LIKE base.