The Japan NBI Expert Team（JNET）大腸拡大Narrow Band Imaging（NBI）分類の紹介

斎藤 豊; 松田 尚久; 中島 健; 坂本 琢; 山田 真善; 斎藤 彰一; 池松 弘朗; 和田 祥城; 岡 志郎; 河野 弘志; 佐野 寧; 田中 信治; 藤井 隆広; 工藤 進英; 浦岡 俊夫; 小林 望; 中村 尚志; 堀田 欣一; 堀松 高博; 坂本 直人; 傅 光義; 鶴田 修; 樫田 博史; 竹内 洋司; 町田 浩久; 日下 利広; 吉田 直久; 平田 一郎; 寺井 毅; 山野 泰穂; 金子 和弘; 山口 裕一郎; 玉井 尚人; 中野（丸山） 尚子; 林 奈那; 岩館 峰雄; 石川 秀樹; 吉田 茂昭; The Japan NBI Expert Team (JNET)

doi:10.11280/gee.58.2314

NBI MAGNIFYING ENDOSCOPIC CLASSIFICATION OF COLORECTAL TUMORS PROPOSED BY THE JAPAN NBI EXPERT TEAM (JNET)

Yutaka SAITO, Takahisa MATSUDA, Takeshi NAKAJIMA, Taku SAKAMOTO, Masayoshi YAMADA, Shoichi SAITO, Hiroaki IKEMATSU, Yoshiki WADA, Shiro OKA, Hiroshi KAWANO, Yasushi SANO, Shinji TANAKA, Takahiro FUJII, Shin-ei KUDO, Toshio URAOKA, Nozomu KOBAYASHI, Hisashi NAKAMURA, Kinichi HOTTA, Takahiro HORIMATSU, Naoto SAKAMOTO, Kuang-I FU, Osamu TSURUTA, Hiroshi KASHIDA, Yoji TAKEUCHI, Hirohisa MACHIDA, Toshihiro KUSAKA, Naohisa YOSHIDA, Ichiro HIRATA, Takeshi TERAI, Hiro-o YAMANO, Kazuhiro KANEKO, Yuichiro YAMAGUCHI, Naoto TAMAI, Naoko NAKANO (MARUYAMA), Nana HAYASHI, Mineo IWATATE, Hideki ISHIKAWA, Shigeaki YOSHIDA, The Japan NBI Expert Team (JNET)

Author information

Yutaka SAITO
National Cancer Center Hospital, Tokyo.
Takahisa MATSUDA
National Cancer Center Hospital, Tokyo.
Takeshi NAKAJIMA
National Cancer Center Hospital, Tokyo.
Taku SAKAMOTO
National Cancer Center Hospital, Tokyo.
Masayoshi YAMADA
National Cancer Center Hospital, Tokyo.
Shoichi SAITO
Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo.
Hiroaki IKEMATSU
National Cancer Center Hospital East, Kashiwa.
Yoshiki WADA
Wada Clinic, Wakayama.
Shiro OKA
Hiroshima University, Hiroshima.
Hiroshi KAWANO
St. Mary’s Hospital, Kurume.
Yasushi SANO
Sano Hospital, Kobe.
Shinji TANAKA
Hiroshima University, Hiroshima.
Takahiro FUJII
Takahiro Fujii Clinic, Tokyo.
Shin-ei KUDO
Showa University, Northern Yokohama Hospital, Yokohama.
Toshio URAOKA
National Hospital Organization Tokyo Medical Center, Tokyo.
Nozomu KOBAYASHI
Tochigi Cancer Center, Utsunomiya.
Hisashi NAKAMURA
Akasaka Endoscopic Clinic, Tokyo.
Kinichi HOTTA
Shizuoka Cancer Center, Shizuoka.
Takahiro HORIMATSU
Kyoto University, Kyoto.
Naoto SAKAMOTO
Juntendo University, Tokyo.
Kuang-I FU
Kamma Memorial Hospital, Tochigi.
Osamu TSURUTA
Kurume University, Kurume.
Hiroshi KASHIDA
Kindai University, Osaka-Sayama.
Yoji TAKEUCHI
Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka.
Hirohisa MACHIDA
Machida Gastrointestinal Hospital, Osaka.
Toshihiro KUSAKA
Kyoto Katsura Hospital, Kyoto.
Naohisa YOSHIDA
Kyoto Prefectural University of Medicine, Kyoto.
Ichiro HIRATA
National Federation of Health Insurance Societies Osaka-Central Hospital.
Takeshi TERAI
Terai Clinic, Tokyo.
Hiro-o YAMANO
Akita Red Cross Hospital, Akita.
Kazuhiro KANEKO
National Cancer Center Hospital East, Kashiwa.
Yuichiro YAMAGUCHI
Tokura Yamaguchi Clinic, Mishima.
Naoto TAMAI
The Jikei University School of Medicine, Tokyo.
Naoko NAKANO (MARUYAMA)
Fujita Health University, Toyoake.
Nana HAYASHI
Hiroshima University, Hiroshima.
Mineo IWATATE
Sano Hospital, Kobe.
Hideki ISHIKAWA
Kyoto Prefectural University of Medicine, Kyoto.
Shigeaki YOSHIDA
Aomori Prefectural Central Hospital, Aomori, Japan.
The Japan NBI Expert Team (JNET)
The Japan NBI Expert Team (JNET)

JOURNAL FREE ACCESS FULL-TEXT HTML

2016 Volume 58 Issue 11 Pages 2314-2322

DOI https://doi.org/10.11280/gee.58.2314

Details

Abstract

Many clinical studies on narrow-band imaging (NBI) have reported the usefulness of NBI magnifying endoscopy for qualitative and quantitative diagnosis of colorectal lesions in Japan. However, critical discussions have raised issues such as i) the presence of multiple terms for similar findings, ii) the necessity of taking into account surface patterns, and iii) differences in NBI findings between elevated (polypoid growth, PG) and superficial lesions (non-polypoid growth, NPG).

The Japan NBI Expert Team (JNET) was constituted with the aim of establishing a universal NBI magnifying endoscopic classification of colorectal tumors (JNET classification) in 2011.

To establish a universal NBI magnifying endoscopic classification of colorectal tumors, the JNET, consisting of 38 NBI expert members, was formed within the “Research Group of the National Cancer Center Research and Development Fund” (Yutaka Saito Group) in 2011.

First, a working group was organized consisting of young but experienced researchers from six institutions in order to establish common evaluation criteria of the JNET classification. Consequently, normal/hyperplastic lesions were classified as type 1, low-grade adenomas as type 2A, high-grade adenomas as type 2B, and deep submucosal invasive cancers as type 3, and a magnifying NBI scale that took into account the vascular and surface patterns was created for both PG and NPG tumors.

A web-based interpretation study was conducted by a JNET member in order to determine the NBI findings and diagnostic criteria to be used in the universal classification system in 2013. A JNET classification system was established based on the results of univariate/multivariate analyses using a modified Delphi method at a consensus meeting on June 6, 2014.

The JNET classification consists of four categories of vessel and surface patterns, i.e., Types 1, 2A, 2B, and 3. Types 1, 2A, 2B, and 3 are correlated with the histopathological findings of hyperplastic polyp/sessile serrated polyp (SSA/P), low-grade intramucosal neoplasia, high-grade intramucosal neoplasia/superficial submucosal invasive cancer, and deep submucosal invasive cancer, respectively.

At present, validation studies for the JNET classification have been proposed to be conducted.

Corresponding author

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