2017 Volume 59 Issue 4 Pages 431-437
A 63-year-old man with a history of gastroesophageal reflux disease presented with heartburn. Gastroscopy revealed a 5-mm, reddish, flat, elevated lesion with erosion in the posterior wall of the body of the stomach. Histological findings of biopsy specimens from the lesion revealed poorly differentiated adenocarcinoma.
Abdominal CT upon admission to our hospital showed a 6-cm right renal mass. The gastric lesion was treated by endoscopic submucosal dissection (ESD). Histological findings of the resected specimens confirmed that metastatic clear cell renal cell carcinoma (RCC) was localized in the mucosal layer of the stomach. Radical nephrectomy was then performed to treat the RCC. Histological findings showed clear cell RCC, G2, Grade 2, v1, ly0, eg, fc0, im0, rc-inf1, rp-inf0, s-inf0, pT3a, pN0, pM1, Stage Ⅳ.
Gastric metastasis of RCC is very rare, and synchronous metastasis localized in the mucosal layer is even more uncommon.