2018 Volume 60 Issue 1 Pages 34-41
A 38-year-old man with a preceding 3- to 4-year history of increased frequency of bowel movements and bloody stools presented at our hospital complaining of persistent abdominal pain. Upper gastrointestinal endoscopy revealed an ulcerative colitis (UC)-like lesion in the stomach and duodenum, while lower gastrointestinal endoscopy revealed UC of the entire colon. Further examination by computed tomography revealed pancreatic enlargement. Examination of biopsy specimens from the pancreas obtained by endoscopic ultrasound fine needle aspiration (EUS-FNA) revealed granulocytic epithelial lesions, leading to the diagnosis of type 2 autoimmune pancreatitis (AIP). UC and AIP were managed by the administration of prednisolone and 5-ASA preparations, after which the lesions resolved. The patient was placed on 5-ASA maintenance therapy and there has been no recurrence. To our knowledge, this is the first report of UC concurrently occurring with upper gastrointestinal lesions and type 2 AIP.
