EFFICACY AND SAFETY OF SELF-EXPANDABLE METALLIC STENT PLACEMENT IN PATIENTS WITH ADVANCED ESOPHAGEAL CARCINOMA IN TERMS OF PROPERTIES OF THE MECHANICAL STENT

Abstract

【Background and Objective】We conducted a retrospective analysis to investigate the efficacy and safety of self-expandable metallic stent (SEMS) placement in terms of properties of the mechanical stent. 【Methods】We examined 42 patients with advanced esophageal carcinoma who underwent placement of a SEMS in our department between January 2008 and August 2016. We classified them according to the absence of radiotherapy, type of SEMS, and efficacy (dysphagia score, period until drinking and dietary intake, overall survival time), and compared adverse events between the groups. 【Results】 The median age was 67.5 years old, and the primary tumor was located at the middle thoracic esophagus in 27 cases (64.2％). There were no significant differences in efficacy and safety between those who did or did not undergo radiation treatment. Although there were no significant differences in efficacy and the incidence of adverse events among the different SEMS types, the incidence of serious adverse event (SAE) was significantly different according to the type of SEMS (P＜0.01). 【Conclusion】 For the effectiveness and safety of SEMS placement, an important consideration is not only whether or not radiotherapy was administered, but also stent selection. To place the SEMS safely, it is important to select a suitable stent for the patient’s condition taking mechanical properties of the SEMS into account.