PROSPECTIVE AND MULTICENTER STUDY OF BOWEL PREPARATION CONSISTING OF POLYETHYLENE GLYCOL THAT CONTAINED ASCORBIC ACID AND GLYCERIN ENEMA FOR COLON CAPSULE ENDOSCOPY

Abstract

Objective: Our objective was to evaluate the effectiveness of polyethylene glycol containing ascorbic acid (Asc-PEG) and glycerin enema (GE) as preparation for colon capsule endoscopy (CCE). Methods: We conducted a prospective multi-center study of patients who were scheduled to undergo CCE using Asc-PEG and GE as preparation. We evaluated visualization of the colon, excretion rate and associated factors, colonic polyp detection rate, and adverse events. Results: Eighty-two patients were analyzed. Adequate visualization of the entire colon was achieved in 82% (67/82). Capsules were excreted in 83% (68/82), and the mean small bowel transit time was significantly shorter in the group with successful excretion than in the group with unsuccessful excretion (p=0.025). GE was used in 27 cases (33%) and induced anus excretion in 78% (21/27) of cases. The colonic polyp detection rate was 49% (40/82). No adverse events were observed. Conclusion: Our regimen using Asc-PEG and GE seems to be a useful and safe preparation method for CCE.