2019 Volume 61 Issue 3 Pages 259-265
A 50-year-old man underwent esophagogastroduodenoscopy for the purpose of screening. A 20 mm, large, type 0-Ⅱc early esophageal cancer was found in the upper thoracic esophagus, and endoscopic submucosal dissection (ESD) was performed. On histopathological examination, the tumor was squamous cell carcinoma invading the pT1a - LPM (lamina propria mucosae), and vascular and vertical invasion were negative, but the horizontal margin was difficult to judge. However, 3 years and 8 months after ESD, he presented with cervical lymphadenopathy as a chief complaint. He was re-examined and was diagnosed with esophageal cancer. Recurrence of multiple metastasis after endoscopic resection of LPM esophageal cancer is relatively rare.