2019 Volume 61 Issue 9 Pages 1663-1669
A 39-year-old woman visited our hospital for the purpose of careful examination due to a high carbohydrate antigen (CA) 19-9 level. Colonoscopy revealed a 40 mm, large, protruding lesion in the ascending colon with an unclear boundary. The surface exhibited a non-neoplastic pit pattern. On endoscopic ultrasonography, it was visualized as a tumor exhibiting low echoes in the 2nd to 4th layers. Laparoscopic ileocolic resection was performed. Histologically, nerve fibers and spindle-shaped cells proliferated diffusely from the lamina propria of the mucosa to the serosa, and large ganglion cells were found inside the tumor. The diagnosis of ganglioneuroma of the ascending colon was made. Colorectal ganglioneuroma that is not accompanied by neurofibromatosis-1 and multiple endocrine neoplasia syndrome is rare, and further accumulation of cases is necessary.
