2021 Volume 63 Issue 6 Pages 1241-1247
A 34-year-old woman presented epigastric pain. Upper endoscopy revealed diffuse distribution of nodular and flat elevations and depressed areas similar to atrophic epithelium in the gastric body. Pathologic examination of the initial biopsy specimens did not lead to a definitive diagnosis. Her symptom was refractory to a proton pump inhibitor. Re-examination by upper endoscopy five years after the initial endoscopy showed expansion of the lesion, and pathologic examination of a biopsy specimen from the lesion revealed deposition of a collagen band below the gastric epithelium which was consistent with collagenous gastritis. Steroid pulse therapy rapidly relieved the clinical symptom. Follow-up endoscopy and biopsy 3.4 years later demonstrated histological remission.