2021 Volume 63 Issue 8 Pages 1495-1500
A 69-year-old man underwent left nephrectomy for left clear cell renal cell carcinoma (pT1bN0M0 Stage I, Fuhrman grade:G2>G1) in 2008. Surgical resections of mediastinal lymph node metastasis and lung metastasis were performed in 2012 and 2013, respectively, and interferon therapy was subsequently continued. In August 2018, the patient developed acute cholecystitis. When upper gastrointestinal endoscopy was performed as a preoperative examination prior to cholecystectomy, a 10-mm reddened, elevated lesion was found near the esophagogastric junction. Histological examination of biopsy specimens led to the diagnosis of metastasis of clear cell renal cell carcinoma. Endoscopic mucosal resection was performed after consultation with the urology department, as local excision of solitary metastatic foci of renal cell carcinoma has been demonstrated to significantly improve prognosis. We present the significance and benefits of endoscopic therapy of metastatic clear cell renal cell carcinoma.