2022 Volume 64 Issue 11 Pages 2385-2390
A 63-year-old woman with a positive result on fecal occult blood testing underwent CS which revealed a submucosal tumor (approximately 5 cm) on the hepatic flexure of the transverse colon. Endoscopy and enema examination revealed a typical lipoma. However, the patient had no specific symptoms; therefore, she was followed up without any treatment. CS performed 42 months after the initial examination (again after a positive result on fecal occult blood testing) revealed an ulcer on the tumor surface, with the size reduced to approximately 1.5 cm. Biopsy could not establish a definitive diagnosis; therefore, considering the malignant nature of the tumor based on its morphology, we performed laparoscopic-assisted resection for diagnostic confirmation. Histopathological evaluation of the resected specimen revealed a lipoma. Tumor morphology changed significantly during the disease course. We report a rare case of a diagnostically challenging colorectal lipoma.