2022 Volume 64 Issue 7 Pages 1346-1351
A 51-year-old woman underwent screening total colonoscopy (TCS), which revealed a flat elevated cecal lesion (20mm) with an unclear margin and a whitish area (15mm) in the central part of the lesion. Magnifying endoscopy revealed microbubbles within the mucous membrane in the whitish area. Histopathological evaluation of biopsy specimens showed uniformly small vacuoles within the superficial lamina propria and cells that were immunonegative for S-100, D2-40, Factor Ⅷ, CD34, CD31, and CD68. Therefore, the lesion was diagnosed as colonic pseudolipomatosis. Follow-up TCS performed 4 months later showed that the lesion had spontaneously disappeared. Considering the optical mechanisms of reflection and scattering, which produce a whitish color, the endoscopic appearance in the present case is attributable to microbubbles. Magnifying endoscopy documented confirmation of microbubbles in the mucous membrane is important for diagnosis of colonic pseudolipomatosis.
